Faculty Directory

Jay, Steven

Jay, Steven

Professor
Fischell Department of Bioengineering
3116 A. James Clark Hall
Website(s):

EDUCATION

  • 2013    Postdoctoral Fellow, Harvard Medical School/MIT
  • 2009    PhD, Yale University
  • 2004    BSBE, University of Georgia

 

 

RESEARCH AREAS

Extracellular vesicles, bacterial therapeutics, drug delivery, biomanufacturing

LAB OVERVIEW

Our research aims to uncover new biological insights towards the design, production, and delivery of biotherapeutics. We are particularly interested in cell-derived products from both humans and bacteria, especially extracellular vesicles (EVs, including exosomes) and bacterial extracellular vesicles (BEVs, including outer membrane vesicles (OMVs)), as well as engineered protein therapeutics and others. We strive to develop new drug delivery and biomanufacturing approaches using fundamental tools from both engineering and biology to address clinical needs across a wide spectrum of applications. Overarching goals of the lab include developing therapeutics towards clinical translation and endowing trainees with the skills and knowledge necessary to become leaders in the biotechnology and pharmaceutical industries.

PUBLICATIONS

Google Scholar Profile


  • BIOE340 - Modeling Physiological Systems 
  • BIOE389C - Bioengineering Design Competitions 
  • BIOE462 - Therapeutic Development and Delivery 
  • BIOE612 - Physiological Evaluation of Bioengineering Designs 

BIOE Students Recognized for Innovative Healthcare Solutions at 2026 Capstone Design Expo

BIOE and BCE students won top honors at the 2026 Capstone Expo for patient care tech innovations.

BIOE Researchers Publish Study Advancing Probiotic Vesicle Therapy for Inflammatory Bowel Disease

Associate Professor Steven Jay and Nicholas Pirolli report new findings that move bacterial vesicle therapies closer to clinical use.

BIOE Students Earn Top Honors for Health Innovation at 2025 Capstone Expo

BIOE and BCE students showcased innovative health tech solutions at the 2025 Capstone Design Expo.

BIOE Ph.D. Graduate Secures TEDCO Funding to Advance Inflammatory Bowel Disease Therapeutics

Recent BIOE Ph.D. graduate Nicholas Pirolli advances IBD therapy with TEDCO Maryland Innovation funding.

Jenna Mueller Receives NSF CAREER Award

The award will support Mueller’s research to develop affordable, accessible technologies for cervical dysplasia in low-income communities around the world.

Four BIOE Terps Awarded NSF Graduate Research Fellowships

Two seniors and two alumni were selected for this prestigious fellowship.

Erika Moore Receives NSF CAREER Award

Incoming BIOE faculty member Erika Moore receives prestigious NSF CAREER Award for immune system research.

24 Teams Present at BIOE Capstone Competition Including First BCE Students

On May 8, 2023, 24 teams presented novel designs at the BIOE Capstone Design Competition.

BIOE Capstone Class Virtually Presents 24 Novel Projects

BIOE seniors present Capstone projects and celebrate winners virtually.

NIH Awards $2.8M Grant to Further Dementia Research

UMB, BIOE researchers team up to study link between spinal cord injury and dementia.

2019 Dean's Doctoral and Master's Student Research Awards

Created by Clark School Dean Darryll Pines, the competition recognize distinguished graduate student researchers in order to help propel their careers and demonstrate the value of high-quality engineering research.

Fischell Department of Bioengineering Launches REU Program

NSF-funded summer program invites undergrads to explore new approaches to engineering cells, tissues, organs.

Natalie Livingston Awarded NSF Graduate Fellowship

BIOE senior recognized for efforts to advance drug delivery research.

Three BIOE Professors Awarded NIH R01s in as Many Months

Drs. Jewell, Scarcelli, and Jay were awarded a collective total of $5.4 million in NIH R01 funding this spring.

Transforming Medicine, Impacting Health

While many freshmen were acclimating to college life, a team of first-year students was adjusting to life as biotech inventors.

Jay Receives National Science Foundation CAREER Award

BIOE assistant professor recognized for efforts to develop new class of biotherapeutics.

Gray Wins Dr. Mabel S. Spencer Award for Graduate Achievement

BIOE Ph.D. student recognized for efforts to develop therapies for diseases of the central nervous system.

John Schardt Awarded American Association of Pharmaceutical Sciences Fellowship

BIOE graduate student recognized for design of multivalent protein therapeutics to target various cancers.

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

Schardt Awarded UMD-NCI Cancer Research Training Fellowship

BioE graduate student recognized for efforts to develop novel molecular engineering approach to breast and ovarian cancer therapy. 

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More

Students' inventions range from diagnostic devices to accident prevention products.

Clark School Welcomes New Faculty

Ten new faculty members join the Clark School for the 2013-2014 school year.

UM Recognizes Robotic Surgery, Virus Filter

Clark School faculty and students earn two Invention of the Year awards.

$50K Business Plan Competition Semifinalists Announced

The 16 semifinalist teams include university faculty, students, and young alumni.

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