Faculty Directory

Kim, Anthony J.

Kim, Anthony J.

Professor, Neurosurgery and Pharmacology (UMSOM)
Adjunct Professor, Fischell Department of Bioengineering
Research Health Scientist, U.S. Department of Veterans Affairs
Co-Director, Translational Therapeutics Research Group
Fischell Department of Bioengineering
University of Maryland School of Medicine
655 W. Baltimore Street, 8-029 Bressler Research Building

Education and Training

Ph.D., Chemical and Biomolecular Engineering, University of Pennsylvania, 2006

Postdoctoral Fellow, University of Pennsylvania, 2007-2009

Postdoctoral Fellow, Johns Hopkins University School of Medicine, 2009-2013 


Selected Honors and Awards

ATIP Innovative Collaborative Project Award, Institute for Clinical and Translational Research, 2024

VA Merit Review Award, 2022

Maryland Innovation Initiative Award, 2019

NIH MERIT Award (R37), 2018

Collaborative MPI Program Award, University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC), 2017

NIH K25 Quantitative Research Career Development Award, 2014-2017

AAPS New Investigator Award, American Association of Pharmaceutical Scientists, 2015    

Genentech/AAPS Innovation in Biotechnology Award, 2015

PhRMA Foundation Research Starter Grant in Pharmaceutics, 2014

NIH F32 NRSA individual Postdoctoral Fellowship, 2011-2013

Wilmer Research Award, 2012

As Director of the Nanotherapeutics Laboratory and Co-Director of the Translational Therapeutics Research Group (TTRG), Dr. Kim's research focuses on developing translational nanomedicine for brain, breast, and other cancers.  This is achieved through a collaborative team of engineers, basic scientists, and clinicians to spur innovation at the interface of bioengineering and clinical medicine.  Towards this goal, his team will (1) identify and characterize the rate-limiting extra- and intracellular barriers by applying innovative biophysical tools and (2) develop advanced therapeutic platforms that overcome these barriers to improve therapeutic outcomes. Dr. Kim has authored ~60 peer-reviewed papers, including publications in Science, Nature Materials, ACS Nano, Science Advances, Journal of the American Chemical Society, Angewandte ChemiePhysical Review Letters, and Biomaterials. His research program has been supported by the National Institutes of Health (NIH), U.S. Department of Veterans Affairs (VA), National Science Foundation (NSF), American Cancer Society (ACS), Elsa U. Pardee Foundation, AAPS Foundation, PhRMA Foundation, TEDCO, FUS Foundation, and others. 

NIH R01 CA269995 (Role: MPI), 12/01/22 - 11/31/27

Nanotherapeutic enhancement of interstitial thermal therapy for glioblastoma


VA I01 BX005770 (Role: PI), 07/01/22 – 06/31/26

Novel drug delivery strategies for treatment of breast cancer brain metastases


NIH R37 CA218617 (Role: PI), 03/01/18 – 02/28/25

Impact of Fn14-targeted Nanoparticles for Triple-Negative Breast Cancer


ATIP Innovative Collaborative Project Award (Role: MPI), 05/01/24 – 5/01/25

Development of Fn14-targeted DART nanotherapeutics for cancer patient clinical trials


Focused Ultrasound Foundation Research Project (Role: Co-I), 06/01/22 – 05/31/23

PET-labeling and Testing of Paclitaxel Nanoformulations with MB-FUS

BIOE447 & BIOE489O: Clinical Experiences in Bioengineering Course, Brain Drug Delivery/Neurosurgery, University of Maryland A. James Clark School of Engineering, 2021, 2022, 2023

GPLS 665 Cancer Biology: From Basic Research to the Clinic, Drug Delivery/Targeting, University of Maryland Graduate School, 2020, 2021, 2022

MSTP Molecules to Medicine (M2M) Course, Nanotechnology for Drug Delivery, University of Maryland School of Medicine, 2021

CIPP 907: Conflicts of Interest in Biomedical Research course, University of Maryland Graduate School, 2015 - present

Highlighted Publications

Carney CP*, Pandey N*, Kapur A, Saadi H, Ong HL, Chen C, Winkles JA, Woodworth GF, Kim AJ. (2023) Impact of targeting moiety type and protein corona formation on the uptake of Fn14-targeted nanoparticles by cancer cells. ACS Nano. 17, 19667

Pandey N, Anastasiadisa P, Carney CP, Kanvinde P, Woodworth GF, Winkles JA, Kim AJ. (2022) Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment. Advanced Drug Delivery Reviews. 188, 114415.

Dancy JG*, Wadajkar AS*, Connolly NP, Galisteo R, Ames HM, Peng S, Tran NL, Goloubeva OG, Woodworth GF, Winkles JA, Kim AJ. (2020) Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer. Science Advances. 6, eaax393.

Wadajkar AS, Dancy JG, Roberts NR, Connolly N, Strickland DK, Winkles JA, Woodworth GF, Kim AJ. (2017) Decreased non-specific adhesivity, receptor targeted (DART) nanoparticles exhibit improved dispersion, cellular uptake, and tumor retention in invasive gliomas. Journal of Controlled Release 267, 144.

Schneider CS, Perez JG, Cheng E, Zhang C, Panagiotis M, Hanes J, Winkles JA, Woodworth GF, Kim AJ. (2015) Minimizing the Non-specific Binding of Nanoparticles to the Brain Enables Active Targeting of Fn14-positive Glioblastoma Cells. Biomaterials. 42, 42.

Kim AJ, Boylan NJ, Suk JS, Hwangbo M, Yu T, Shuster BS, Cebotaru L, Lesniak, WG, Oh JS, Adstamongkonkul P, Choi AY, Kannan RM, Hanes J. (2013) Use of Single-Site Functional PEG-Dendrons to Prepare Gene Vectors that Penetrate Human Mucus Barriers. Angewandte Chemie Int Ed. 52, 3985.

Kim AJ, Scarlett R, Biancaniello PL, Sinno TR, Crocker JC. (2009) Probing interfacial equilibration in microsphere crystals formed by DNA-directed assembly. Nature Materials. 8, 52.

Kim AJ, Manoharan VN, Crocker JC. (2005) Swelling-Based Method for Preparing Stable, Functionalized Polymer Colloids. Journal of the American Chemical Society. 127, 1592.


Find a complete list of Dr. Kim's publications on his Google Scholar Page

Dean's Circle Spotlight: A Blueprint for Human-Oriented Innovation

Anthony Ephremides, the founder of the field of ad-hoc wireless networks, is one of Maryland Engineering's most philanthropic faculty members.

Inaugural UMD Neuro-Link Grant Supports Glioblastoma Research

Funding pathway promotes high-impact collaborations between UMB's neurosurgery and UMCP's bioengineering.

Engineering Graduate Students Win UMD 3MT Competition

Three Clark School graduate students were among the university's 2020 Three Minute Thesis (3MT) winners.

Four BIOE Ph.D. Students Awarded NIH Fellowships

Students recognized for research in vaccine design, surgical sealants, pulmonary diseases, and multiple sclerosis. 

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

Ephremides Wins IEEE MILCOM Lifetime Achievement Award

Professor Ephremides named 2014 IEEE MILCOM Technical Lifetime Achievement Award Recipient for his contributions to military communications.

Ephremides Honored for Communications Work

Electrical and computer engineering professor recognized as a significant contributor to ad hoc and sensor networks field.

Ephremides Named Distinguished University Professor

ECE Professor receives highest academic honor conferred by the University of Maryland.

Melchiorri Named 2011 Fischell Fellow

Incoming graduate student specializes in cardiovascular research.

NSF Grant for Ephremides

Funding for research on "Cooperative Networking Across the Layers."

Ephremides Establishes Chair Professorship

ECE professor "gives back" to the Clark School.

Pioneering MTECH Celebrates 20 Years Linking the Clark School and Business

This week the Maryland Technology Enterprise Institute (MTECH) celebrated its 20th anniversary and was honored for its pioneering and ever-growing services that link Clark School capabilities and the needs of the business world. The celebration was held in the new Jeong H. Kim Engineering Building.

Professor Anthony Ephremides is appointed the Cynthia Kim Professor in Information Technology

Effective August 23, 2003, Professor Anthony Ephremides is appointed the Cynthia Kim Professor in Information Technology.

Clark School Accomplishments Spring 2002

A list of Clark school accomplishments for Spring 2002